Kitty was born in 1948 in Yuendumu, 300 kilometres north west of Alice Springs, Northern Territory. At the age of 10, Kitty and her family were re-settled at Lajamanu. She grew up as a traditional desert walker around the Tanami Desert region - a desert filled with vivid colour. Her experiences here and knowledge of traditional culture can be seen in the defining colours she uses in her work, reflecting the flowers, sky and salt bed of Lake Mackay, seen in her Mina Mina Dreaming paintings. Mina Mina is a salt lake and sacred site for Walpiri women. Kitty Napanangka Simon is a senior custodian and keeper of womens' Law for this remote and isolated desert landscape, and Mina Mina is the subject of many of her paintings.
Napanangka works with a variety of traditional and contemporary art mediums including body paintings in ochre and acrylic on linen and canvas. She is a very traditional lady who understands her culture. Her family come from Lake Mackay area. She was born in Yuendumu and arrived in Lajamanu at 10 years of age. Napanangka enjoys painting as it is a social activity in Lajamanu. Her experiences of travelling through the desert and life in Lajamanu coupled with knowledge of culture is now shown in defining colours and styles. Kitty uses a mixture of line work, coming from body art and ceremony, and intricate dot work.